The purpose of this study was to investigate the effect of Gleditsiae Spina on the pro life-ration of human cancer cell-lines.
The effects of Gleditsiae Spina on the proliferation of A 431, HeLa. MOLT-4 K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay.
@ES The results were as follows:
@EN 1. Gleditsiae Spina increased the proliferation of HeLa, MOLT-4 and K562 cells.
2. The cytotoxicity of micomycin C on K562 cells was increased by the combination of Gleditsiae Spina.
3. Gleditsiae Spina did not effect the proliferation of Balb/c 3T3 cells.
4. Gleditsiae Spina stimulated the proliferation of thymocytes.
5. Gleditsiae Spina stimulated the proliferation of splenocytes.
6. Gleditsiae Spina stimulated the proliferation of human lymphocytes
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